Problems Confronted by Big Pharma and Their Solutions Composition

Since 2000 the Wall street game valuation with the ‘Big Pharma' companies offers dropped sharply. Discuss the causes of the pharmaceutical industry's current problems and steps that companies are acquiring to deal with them.

By Ali Asgar Kagzi

In 1990s, pharmaceutical companies were one of the leading shareholder value makers at the stock market. By 1998 the P/E ratio with the Big Pharma companies was twice regarding the global stock exchange and there is a sudden run among the shareholders to have a reveal of the Pharma pie. Nevertheless according to the Harvard Business Review, May 2008, from December 2000 to February 2008 the top 15 companies shed approximately $850 billion in shareholder benefit and the price of their shares fell by 32 instances earnings, normally, to 13. This shows that something went gravely wrong. The following sections would spotlight the reasons responsible for the industry's tumble for the stock market as well as the steps the pharma companies have been acquiring to gain back their earnings and reputation.

Though the utilization of drugs dates back to the ninth century, the pharmaceutical industry came into existence just during the after 19th 100 years. Minimal study was carried out using old fashioned methods and little expansion occurred till the the middle of 20th century. The discovery of Penicillin by Alexander Fleming in 1928 was a major breakthrough. But it had not been produced from the commercial perspective and utilized mainly for the goal of carrying out lab experiments. The widespread employ and progress Penicillin throughout the World War II exposed new paths for the pharmaceutical market. The conditions following the World War II even more facilitated the industry's development. The battle exposed various diseases that no drug existed, thus providing adequate opportunities to get research and development. In addition , public understanding and support for health-related research boomed and general public funding elevated dramatically. The period from 1950 – 1990 can be known as a fantastic period for the sector with substantial R& D programs undertaken and a tide of new drugs launched in the market. It really is noteworthy that the national organizations played an eminent position in the advancement pharmaceutical market in a particular country. Policies for perceptive property security, drug authorization, and costs played a crucial role inside the industry's advancement. Consequently, UNITED STATES dominated the industry with firms including Merck, Eli Lilly and Pfizer growing rapidly and profitably. They will invested huge amounts in R& D and developed medicines termed as " blockbuster” which in turn enabled them to earn large profits. Comprehensive patenting secured these companies through the generic drug manufacturers and there was virtually no marketplace for the generics. In 1980, only 2% from the US drug market occured by generics. " Between 1980 and 1992 pharma stocks rose by 959%, compared to a rise of 386% in the S& P index. ” (Ravenscraft et al, 2000, p292). But the desire run in the pharma corporations was not to last long. The 21st century brought a number of challenges for the industry and it was left grappling pertaining to solutions. The investors began to lose assurance and the true market value of the pharmaceutical drug companies decreased. (Henderson ainsi que al, 1999)

The beginning of the 21st century saw a downfall inside the profits with the Big Pharma companies. That they faced a number of problems such as pressure to lower drug rates, decline in R& M productivity, over-dependence on particular blockbuster drugs and obvious expiry of these drugs soon, and competition from the new and rising biotech organizations. The total effect of these kinds of factors was disastrous and promote prices in the pharma businesses plunged. Big Pharmas' typical P/E proportion declined drastically by about 40% in the period between 2k and 2002 and continued to be at decrease levels through 2004 (see figure 1)


Till 1980s the pharmaceutical firms enjoyed prices flexibility as a result of way the drugs had been sold and there was lack of government...

References: 1 . Business Standard, Tatas' Advinus in order to even this coming year, October two, 2008,


15. The Mom or dad, Drug Firms: Big Pharma besieged by all sides, August 30, 08

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